CD34+ megakaryoblastic leukaemic cells are CD38−, but CD61+ and glycophorin A+: improved criteria for diagnosis of AML-M7?
نویسندگان
چکیده
منابع مشابه
Acute Megakaryoblastic Leukaemia (AML M7): Rare association of Down syndrome and Haemoglobin E-Beta Thalassaemia
Acute megakaryoblastic leukemia(AML-M7) is a rare type of pediatric AML. It represents approximately 1% of all leukemias during childhood & has an incidence of 0.5% per million per year. In young children with Down syndrome, AML-M7 is the most common type of AML. There is no association reported till date in between Down syndrome & Haemoglobin E-Beta thalassaemia. In our case we got rare associ...
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A 39-year-old woman was diagnosed as having immune thrombocytopenia (ITP) in 1981 in another hospital, and she was well controlled with prednisolone. No other immunosuppressive drugs, such as cyclosporine or azathioprine, were used. In 1997, she was diagnosed as having acute megakaryoblastic leukemia (AML-M7) in another hospital. Blasts showed the absence of peroxidase (POX) and positive platel...
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Many investigators have used xenogeneic, especially murine stromal cells and fetal calf serum to maintain and expand human stem cells. The proliferation and expansion of human hematopoietic stem cells in ex vivo culture were examined with the goal of generating a suitable protocol for expanding hematopoietic stem cells for patient transplantation. Using primary fetal liver cells, we established...
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Flt3 ligand (FL) has been proposed as a possible modulator hanced or depleted the number of precommitted cells in expansion culture, CD34 CD38 and HLA-DR fractions of early hematopoietic cell growth. The purpose of this study was to analyze the impact of FL on ex vivo expansion of were incubated in liquid culture and analyzed by flow cytometry. Inclusion of FL enhanced the absolute number of pr...
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ژورنال
عنوان ژورنال: Leukemia
سال: 1997
ISSN: 0887-6924,1476-5551
DOI: 10.1038/sj.leu.2400648